FODZYME® 60-dose Home Kit

FODZYME® Home Kit breaks down fructan, lactose, and GOS, helps you enjoy your favorite meals painlessly, and comes in a sustainable jar.


$81.25
$81.25
Ingredients: fructan hydrolase, lactase, alpha-galactosidase, dextrose, dextrin, and maltodextrin.

Life-changing results through a targeted approach

We designed a blend of natural enzymes that break down the most common gut symptom triggers like FODMAPs, including lactose, galacto-oligosaccharides (GOS), and fructans.

  • powder activates the moment it hits your plate
  • exclusive fructan hydrolase formulation breaks down fructan
  • FODMAPs are destroyed before causing symptoms
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Sprinkle to make food painless

Adding directly to meals high in fructan, GOS, and lactose brings the best results. It's not rocket science.

How it works
How it works

Highly specialized enzymes

We created a unique blend of enzymes designed specifically to break down the FODMAP molecules

fructan hydrolase enzyme binds specifically to fructans and break them down to simple easy-to-digest fructose and glucose molecules

alpha-galactosidase enzyme binds specifically galacto-oligosaccharides (GOS) and break them down to simple easy-to-digest galactose, fructose, and glucose molecules

Lactase enzyme binds specifically to lactose molecule and break it down to simple easy-to-digest sugars, glucose and galactose

Science behind FODZYME

SHIME® experiment

a scientifically validated model of a human gut.

Enzymatic digestion

in simulated gastric conditions with FODZYME

Decrease of Gas

production in model GI tract with FODZYME

SCFA Production

Short-chain fatty acid production is lower yet preserved

Powder vs capsules

Specific mode of administration for optiomal integration

We tested FODZYME in SHIME®, a multi-compartment scientifically validated model of the complete human gut, to study the efficacy of FODZYME’s fructan hydrolase in fructan degradation.

A dose of FODZYME was added together with 3g of inulin (a common source of fructan) to see how effectively FODZYME’s fructan hydrolase breaks down fructan.

Findings indicated rapid breakdown of fructan to fructose in gastric conditions with ~90% of the inulin mass converted to fructose within 30 minutes thus demonstrating resilience to both gastric pH and protease activity.

Further intestinal modeling demonstrated a significant portion of the released fructose was absorbed during simulated small intestinal transit (70%), with a corresponding decrease in microbial gas production.

SCFA production was reduced but not depleted, suggesting FODZYME’s enzymatic approach may be more favorable to colonic health than avoiding FODMAPs altogether [4].

It is critical for the enzyme to distribute in the ingested food bolus as quickly as possible to take advantage of the optimal pH range for enzymatic activity immediately following a meal. Later on, gastric pepsin becomes considerably more active and other proteases threaten enzyme stability.

FODZYME’s powder formulation maximizes homogenization of enzymes and food and thus the availability of enzymes to their substrates at the post-prandial gastric pH most favorable to microbial carbohyrases.

Science behind FODZYME

SHIME® experiment

a scientifically validated model of a human gut.

We tested FODZYME in SHIME®, a multi-compartment scientifically validated model of the complete human gut, to study the efficacy of FODZYME’s fructan hydrolase in fructan degradation.

Enzymatic digestion

in simulated gastric conditions with FODZYME

A dose of FODZYME was added together with 3g of inulin (a common source of fructan) to see how effectively FODZYME’s fructan hydrolase breaks down fructan.

Findings indicated rapid breakdown of fructan to fructose in gastric conditions with ~90% of the inulin mass converted to fructose within 30 minutes thus demonstrating resilience to both gastric pH and protease activity.

Decrease of Gas

production in model GI tract with FODZYME

Further intestinal modeling demonstrated a significant portion of the released fructose was absorbed during simulated small intestinal transit (70%), with a corresponding decrease in microbial gas production.

SCFA Production

Short-chain fatty acid production is lower yet preserved

SCFA production was reduced but not depleted, suggesting FODZYME’s enzymatic approach may be more favorable to colonic health than avoiding FODMAPs altogether [4].

Powder vs capsules

Specific mode of administration for optiomal integration

It is critical for the enzyme to distribute in the ingested food bolus as quickly as possible to take advantage of the optimal pH range for enzymatic activity immediately following a meal. Later on, gastric pepsin becomes considerably more active and other proteases threaten enzyme stability.

FODZYME’s powder formulation maximizes homogenization of enzymes and food and thus the availability of enzymes to their substrates at the post-prandial gastric pH most favorable to microbial carbohyrases.

Foods that FODZYME works with (and not)

See the foods high in specific FODMAPs and make sure not to use FODZYME on foods high in polyols. See the full list certified by the Monash University below.

FULL FODMAP LIST

✔️ Fructan and GOS

Almonds Artichoke Baby spinach Banana Beans Beetroot Blueberries Broccoli Brussels sprouts Cabbage (red and savoy) Cashews Chickpeas Cranberries Dates Figs Garlic Grapefruit Leek Lentils Onion Peas Pistachios Pomegranate Raspberries Roma Tomatoes Scallion Shallots Silken tofu Wheat Zucchini

✔️ Products high in lactose

Buttermilk Cheese, Queso Fresco Cottage cheese Cream Creamy cheeses Custard Goats cheese Haloumi Ice-cream Kefir Milk Paneer Quark cheese Ricotta cheese Sour cream Yoghurt

🙅 Foods rich in polyols (currently not compatible with FODZYME)

Apple Apricot Avocado Blackberries Cauliflower Celery Cherries Lychee Mushrooms Nectarine Peach Pear Plum Prune Sauerkraut Sweetcorn Sweet potato

Formulation

All ingredients are sourced from a US-based manufacturer. They are mixed and packed in a US-based cGMP FDA-registered facility.
Serving size 1/4 tsp (750 mg)
enzyme blend (fructan hydrolase, lactase, alpha-galactosidase) 24 mg per serving

Other ingredients: dextrose, dextrin, maltodextrin.

All-natural formula with a real therapeutic potential

Fodzyme Others
Fructan degradation
GOS degradation
Lactose degradation
superior enzyme activity
Designed for Maximum enzyme Distribution
verified across in vitro studies
Clinically Validated In House
Third-party tested for allergens and toxic residues
PORTABLE FORMAT FOR ON-THE-GO USAGE

*To evaluate the activity of our enzymes in the stomach, we use a Simulator of the Human Intestinal Microbial Ecosystem, an in vitro model of the human gut.

Make FODZYME work for you

Though individual results may vary, adding a recommended dose of FODZYME to a high-FODMAP meal helps most people significantly.

1. Sprinkle

Cover your meal with the FODZYME powder evenly to help it integrate with your food.

2. STIR

Give your food a good mix if you can. Otherwise, a full dose on the first bite will work just as well!

3. savor

Indulge in your favorite flavors with confidence and forget about the fear of FODMAPs.

FAQs

Here's everything you need to know to make the best out of your FODZYME experience.

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Product

What is FODZYME®?

FODZYME® is the first solution to target FODMAP molecules directly. FODZYME® is a novel enzyme preparation designed to tackle lactose, galacto-oligosaccharides, and fructans. These carbohydrate molecules are present in the most common and nutritious foods and are by far the biggest gut troublemakers — especially for individuals who suffer from conditions like Irritable Bowel Syndrome. We are also working on a novel polyol-degrading product to complete the FODMAP family.

What is the list of ingredients?

FODZYME®  INGREDIENTS: Fructan hydrolase, Lactase, Alpha-galactosidase, dextrose*, dextrin*, maltodextrin*.     *to stabilize the enzymes 
CONTAINS NO: gluten, GMOs, milk, casein, soy, egg, artificial colors or flavors
Made in the USA . Never tested on animals. 

What does FODZYME® taste like?

FODZYME is virtually tasteless and does not change the texture of food. Some people with sensitive taste buds note a slight sweetness. That's the sweet taste of being able to eat your favorite foods again!

Who should take FODZYME®? Will FODZYME® work for me?

FODZYME® is meant for adult humans ages 18+. FODZYME does not target specific conditions — rather, FODZYME's enzymes break down triggering substances (fermentable fibers) that are known to ferment by gut bacteria. Specifically, FODZYME's enzymes break down the fibers fructan, galacto-oligosaccharides (GOS), and lactose. So, if you know that you are sensitive to foods that contain them, then we recommend you give FODZYME a shot once your doctor approves you adding a new supplement to your gut-health regimen. 

Can I use FODZYME while pregnant or breastfeeding?

There is no information to indicate that FODZYME® is unsafe for use during pregnancy or breastfeeding. That said, we recommend that people who are pregnant or breastfeeding reach out to their physician before using FODZYME®.

We care deeply about the safety and science behind FODZYME®. All of our ingredients are Generally Regarded As Safe (GRAS) by the FDA. Additionally, Kiwi Biosciences completes third-party lab testing for heavy metals, microbes, and other contaminants to ensure quality and safety.

Enzyme Science

Why is FODZYME® a powder when most enzyme products are in a capsule/caplet?

We love being asked this question because we get to geek out about our discoveries! We know from extensive testing that mixing enzymes directly into food is the most effective way to deliver an enzyme supplement. 

This is because the enzymes need to mix well with the food to get to its substrates (e.g. fructan) within the food. Swallowing an enzyme supplement like a pill/capsule does not allow the enzyme to sufficiently work into the food! The enzymes in pill form remain localized until it is too late: the pH of your gastric tract becomes unfavorable for the enzymes to work or the enzymes become digested themselves. It is crucial to maximize food-enzyme-homogenization, and this is what our powder form achieves.

Subscription

What does my monthly FODZYME® subscription include?

Your subscription includes a 60-dose supply of FODZYME®. 

Edit, skip, or cancel your order at any time. Change your frequency to whatever you want.  Seriously. It's easy. 

The first month of your subscription will come with a lightweight PET Jar. Keep this jar! Your second month will come with a sustainable, home compostable bio-based refill pouch that you can pour into your clean jar. 

Free shipping for US subscribers, flat rate for internationals. 

How much does FODZYME® cost?

FODZYME® is $65 for 60 doses on a no-commitment subscription. Most of our users say they would pay more than $2 a meal to be able to enjoy all restricted foods. 

How do I manage my subscription?

Shipping

Do you ship internationally?

We are working hard to make FODZYME available to as many humans as possible, regardless of their location. At this time we can ship to the United States, Australia, New Zealand, UK, Canada, Belgium, Brazil,  Netherlands, Poland, Austria, Germany, Czechia, Slovakia, Switzerland, United Arab Emirates, Israel, Italy, Denmark, Sweden, Finland, Norway and France. We currently offer $10 flat rate international shipping to the United Kingdom and Canada for orders over $50. Otherwise, international shipping rates vary and are reflected at checkout once the destination is selected. You can also change the country/region to see prices in your currency at the bottom/left side of our website. For customers in Australia and New Zealand, we recently launched an exciting partnership with FodShop. In case you are not familiar, FodShop is the world’s first online FODMAP expert Commercial Nutritionist-run shop and gastroenterology resource, supplying more than 2,000 low FODMAP approved food products from more than 500 local & international brands, additionally meeting various food intolerance, allergen-friendly, and nutrition requirements. Feel free to email us at hello@fodzyme.com if you have any questions.

Usage

Does FODZYME® work with liquids?

Yes, if the liquid contains FODMAPs!

Ex: milk, smoothies, beet juice, wheat beer, etc.You can use FODZYME on liquids that contain FODMAPs (fructan, GOS or lactose).  Just mix FODZYME into liquids that contain FODMAPs and let sit for 5 minutes, then drink.  This gives the enzymes a head start and chance to work.

You can also do this with hot liquids like broth and soups!

FODZYME doesn't work well if you just drink it with water - there are no FODMAPs to breakdown.

What if I can’t mix FODZYME® into my food?

Good question! If your can't sprinkle FODZYME all over or mix it in, you can apply the enzymes to the first bite and chew well. This can be used on foods like burritos, granola bars, and much more. We call this the first bite technique. There should be enough enzyme activity to last through the rest of the meal, even if you chew all the enzymes in the first bite.

Many foods have a couple ways to apply FODZYME. Experiment and see what works best for you!

Example: Two ways to eat a slice of pizza 🍕
  1. 1. Sprinkle FODZYME all over the top like parmesan cheese or red pepper flakes.
  2. 2. Chew well and enjoy.Apply the full scoop to the tip of the pizza and enjoy.


Want to see this in action? Here's a tik tok on how to eat a sandwich with FODZYME. 🥪

How should I test FODZYME® for the first time?

Are you new to the low FODMAP diet and still trying to figure out your trigger foods?

Here’s a helpful video to get you started. We recommend sprinkling 1 dose of FODZYME on the foods you were planning on eating anyway and seeing how you feel. Note if you see a reduction in symptoms such as bloating, abdominal pain, excessive gas, changes in bowel movements, etc. Please keep in mind, FODZYME will not help if you are sensitive to polyols. 

Are you are familiar with the low FODMAP diet and know your triggers?

This video will help get you started. If you know your triggers well, we recommend you try FODZYME by starting with a meal or snack that doesn’t trigger your symptoms and adding 1 high FODMAP food you want to add back into your diet. Example: Add a small portion of grilled onions to a low FODMAP meal. See how you feel over the next day or so. If that test goes well, add two triggers (like onions and some beans) to a low FODMAP meal or a larger serving of a single trigger food. If that goes well, feel free to try FODZYME on a high FODMAP meal with multiple triggers, like pasta or pizza!

Remember you can always increase your dose to 1.5 or 2 scoops if eating very high FODMAP foods or you are particularly sensitive to a certain food.